Antifungal drug susceptibility testing of dermatophytes: Laboratory findings to clinical implications
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چکیده
منابع مشابه
Antifungal Susceptibility Testing: Current Role from the Clinical Laboratory Perspective
Despite availability of many antifungal agents, antifungal clinical resistance occurs, perhaps as a consequence of an infecting organism found to be resistant in vitro to one or more antifungals tested. From what derives the important current role of the in vitro antifungal susceptibility testing (AFST), that is to determine which agents are like to be scarcely effective for a given infection. ...
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G.S. Hall (ed.), Interactions of Yeasts, Moulds, and Antifungal Agents: How to Detect Resistance, DOI 10.1007/978-1-59745-134-5_2, © Springer Science+Business Media, LLC 2012 Abstract Antifungal susceptibility testing has become an important tool for physicians faced with making diffi cult treatment decisions regarding treatment of patients with fungal infections. The Clinical Laboratory and St...
متن کاملAntifungal susceptibility testing of dermatophytes: establishing a medium for inducing conidial growth and evaluation of susceptibility of clinical isolates.
A standardized reference method for dermatophyte in vitro susceptibility testing is lacking. In a previous study, Norris et al. (H. A. Norris, B. E. Elewski, and M. A. Ghannoum, J. Am. Acad. Dermatol. 40(6, part 2):S9-S13) established the optimal medium and other growth variables. However, the earlier study did not address two issues: (i) selection of an optimal medium for conidial formation by...
متن کاملMultilaboratory Evaluation of In Vitro Antifungal Susceptibility Testing of Dermatophytes for ME1111.
ME1111 is a novel small molecule antifungal agent under development for the topical treatment of onychomycosis. Standardization of the susceptibility testing method for this candidate antifungal is needed. Toward this end, 8 independent laboratories determined the interlaboratory reproducibility of ME1111 susceptibility testing. In addition, we subsequently identified 2 strains as quality contr...
متن کاملComparison of disk diffusion method and broth microdilution method for antifungal susceptibility testing of dermatophytes.
The use of the agar diffusion Neo-Sensitabs method to determine antifungal susceptibility of 59 isolates of dermatophytes, namely Epidermophyton floccosum, Microsporum canis, M. gypseum, Trichophyton mentagrophytes, T. rubrum and T. tonsurans to Clotrimazole (CLZ), Itraconazole (ITZ) and Terbinafine (TBF) is described. Results obtained are compared to the minimum inhibitory concentrations (MIC)...
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ژورنال
عنوان ژورنال: Indian Dermatology Online Journal
سال: 2019
ISSN: 2229-5178
DOI: 10.4103/idoj.idoj_146_19